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★One Health Relay Report #2★

2020/02/03


About “Inflammatory colorectal polyps in Miniature dachshunds”

 

Profile #2: Dr. Hiroshi Ohta, Lecturer, Clinical Sciences

 

Inflammatory colorectal polyps (ICRPs) in Miniature dachshunds are characterized by the formation of multiple inflammatory polyps in the colorectal area and are thought to be a breed specific canine inflammatory bowel disease in Japan. We previously reported that T helper cell cytokines, such as interleukin-17, and chemokines are upregulated in polyp lesions of dogs with ICRPs. Now, we try to identify the causative single nucleotide polymorphism for ICRPs using whole-exome sequencing analysis.